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Monday, October 15, 2007

What Are Normal Blood Glucose And Blood Sugar Levels

This is the question my diabetic patients always ask. There are various methods to determine blood glucose level. Some tests give you accurate diagnosis of diabetes or pre-diabetes, while others will tell you how well you are managing your diabetes.

Fasting Blood Sugar Test:
Measures the blood sugar level after 8 hours fast or overnight. Normal fasting blood glucose level is less than 100mg/dl. If your fasting blood glucose level is from 100mg/dl to 125mg/dl then you will have impaired blood glucose level also known as Pre-Diabetes. If your blood glucose level is above 125mg/dl then your doctor will diagnose as a patient of diabetes. To confirm the diagnosis, your doctor may repeat the fasting blood glucose test on any other day. If you have blood glucose level of 126mg/dl or higher in two consecutive tests, then you may have diabetes. If you have blood glucose level greater than 200mg/dl and you have symptoms of diabetes like increased thirst or hunger, frequent urination, weight loss, blurred vision etc, then you may be diagnosed with diabetes mellitus without confirming it with second test.

Random Blood Glucose Test:
Random blood Glucose test gives your blood sugar at any time in a day. Normal random blood sugar level should be less than 200mg/dl. If your random blood glucose level is between 140mg/dl to 200mg/dl then you will have pre-diabetes.

Oral glucose tolerance test
This test measures your response to sugar. First we measure fasting blood glucose level, and then glucose solution is given, after that we measure blood glucose after 1 hour and 2hours. A normal blood glucose level after an oral glucose tolerance test is less than 140 mg/dL. Level between 140 mg/dL to 199 mg/dL suggests pre-diabetes. A blood glucose level of 200 mg/dL or higher two hours after you drink the glucose solution may suggest that you have diabetes mellitus.

Glycated hemoglobin (A1C) test
This test is not for diagnosing diabetes, but it shows you how well you have controlled your sugar in last 2 or 3 months. Normal value is less than 7%, however if it is more than 7 then you and your doctor should think of changing your treatment of diabetes.

Recent Discovery A Breakthrough For Texans Concerned About Diabetes?

British researchers believe they may have found a molecule that can “taste sweets.” This breakthrough could lead to better lines of treatment for the hundreds of thousands of diabetics who live in Dallas, Houston, Austin and elsewhere in the state of Texas.

You could call it a “gut feeling”, but scientists carrying out research into diabetes say they have found that a sweet taste receptor, one which senses sugar and sweeteners, is not only present in the human tongue, but also in the human intestine.

Now these researchers are trying to harness its power and utilize it like a “dimmer switch.” These researchers believe this finding could lead to improved treatment for diabetes, which causes blood sugar levels to become chronically higher than normal.

Professor Soraya Shirazi-Beechey, from the University of Liverpool’s Faculty of Veterinary Science, announced the molecule’s discovery in the intestine.

Shirazi-Beechey said that the researchers found that the sweet taste receptor and the taste protein, which is called gustducin, are present as taste cells in the intestines. These sweet sensing proteins allow both humans and animals to detect sugar or glucose within the intestine.

The doctor explains, “We discovered that mice missing the gene for either of these proteins were unable to process the production of the intestinal sugar and were therefore unable to regulate the intestinal capacity to absorb dietary sugars.”

This is a critical breakthrough because the molecule determines how much sugar the human body absorbs. If scientists can discover how to manipulate this “sweet tasting” molecule, then they can control how much sugar is absorbed by the intestine. “Once it identifies the sweets, it sends signals to another molecule that regulates the levels of sugar taken into the body,” she said. “For example, with a dimmer switch you can control the level of light in the room. That’s what we are trying to do. We are trying to control the switch, the molecule, to increase or decrease the amount of sugar that is absorbed by the body.”

Shirazi-Beechey adds that those who use an artificial sweetener and think they are going to lose weight are sorely mistaken. “Surprisingly we also found that the receptor was able to detect artificial sweeteners in foods and drinks resulting in increased capacity of the intestine to absorb dietary sugars, which would explain why these sweeteners are unsuccessful at helping people lose weight,” she explained.

Prof Shirazi-Beechey and her team are currently working on a food supplement that may be able to control the molecule. Tests are being carried out on mice with the study is still in its early stages.

Scientists are also reporting that, besides a possible cure for diabetes, the ability to control this molecule can help those with obesity. As a side note for horse racing fans, it could help racehorses retain a high level of sugar to sustain them for long races.

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